{"id":1030,"date":"2023-09-08T23:58:44","date_gmt":"2023-09-08T15:58:44","guid":{"rendered":"https:\/\/incob.apbionet.org\/incob23\/?post_type=product&#038;p=1030"},"modified":"2023-11-09T18:41:05","modified_gmt":"2023-11-09T10:41:05","slug":"workshop-introduction-to-machine-learning-in-bioinformatics","status":"publish","type":"product","link":"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/","title":{"rendered":"Workshop 2 &#8211; Introduction to Machine Learning in Bioinformatics"},"content":{"rendered":"<p><strong>Abstract<\/strong><br \/>\nThe emerging field of Genome-NLP (Natural Language Processing) aims to analyse biological sequence data using machine learning (ML), offering significant advancements in data-driven diagnostics. Three key challenges exist in Genome-NLP. First, long biomolecular sequences require \u201dtokenisation\u201d into smaller subunits, which is non-trivial since many biological \u201dwords\u201d remain unknown. Second, ML methods are highly nuanced, reducing interoperability and usability. Third, comparing models and reproducing results are difficult due to the large volume and poor quality of biological data. To tackle these challenges, we developed the first automated Genome-NLP workflow that integrates feature engineering and ML techniques. The workflow is designed to be species and sequence agnostic.<\/p>\n<p>In this workflow:<\/p>\n<p>a) We introduce a new transformer-based model for genomes called genomicBERT, which empirically tokenises sequences while retaining biological context. This approach minimises manual preprocessing, reduces vocabulary sizes, and effectively handles out-of-vocabulary \u201dwords\u201d.<br \/>\n(b) We enable the comparison of ML model performance even in the absence of raw data. To facilitate widespread adoption and collaboration, we have made genomicBERT available as part of the publicly accessible conda package called genomeNLP. We have successfully demonstrated the application of genomeNLP on multiple case studies, showcasing its effectiveness in the field of Genome-NLP<\/p>\n","protected":false},"excerpt":{"rendered":"<p>12th November 2023, 1300 &#8211; 1700, Room 2003, TRI<\/p>\n","protected":false},"featured_media":1038,"template":"","meta":[],"product_cat":[23],"product_tag":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Workshop 2 - Introduction to Machine Learning in Bioinformatics - The 22nd International Conference on Bioinformatics (InCoB 2023)<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Workshop 2 - Introduction to Machine Learning in Bioinformatics - The 22nd International Conference on Bioinformatics (InCoB 2023)\" \/>\n<meta property=\"og:description\" content=\"12th November 2023, 1300 - 1700, Room 2003, TRI\" \/>\n<meta property=\"og:url\" content=\"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/\" \/>\n<meta property=\"og:site_name\" content=\"The 22nd International Conference on Bioinformatics (InCoB 2023)\" \/>\n<meta property=\"article:publisher\" content=\"http:\/\/facebook.com\/apbionet\" \/>\n<meta property=\"article:modified_time\" content=\"2023-11-09T10:41:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/incob.apbionet.org\/incob23\/wp-content\/uploads\/2023\/09\/craiyon_010836_BIOINFORMATICS.png\" \/>\n\t<meta property=\"og:image:width\" content=\"256\" \/>\n\t<meta property=\"og:image:height\" content=\"256\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@apbionetorg\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/\",\"url\":\"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/\",\"name\":\"Workshop 2 - Introduction to Machine Learning in Bioinformatics - The 22nd International Conference on Bioinformatics (InCoB 2023)\",\"isPartOf\":{\"@id\":\"https:\/\/incob.apbionet.org\/incob23\/#website\"},\"datePublished\":\"2023-09-08T15:58:44+00:00\",\"dateModified\":\"2023-11-09T10:41:05+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/incob.apbionet.org\/incob23\/product\/workshop-introduction-to-machine-learning-in-bioinformatics\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/incob.apbionet.org\/incob23\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Shop\",\"item\":\"https:\/\/incob.apbionet.org\/incob23\/shop\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Workshop 2 &#8211; 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