Whole Genome Sequencing Data Analysis

Yang Cheng

Roche 454 GS Data Analysis Software package provides point-and-click tools for data processing, mapping, de novo assembly and amplicon variant analysis.

GS De Novo Assembler uses newbler algorithm to perform whole genome assembly with shotgun reads alone (in *.sff, *.fna or *.fastq formats) or in combination with 3,8, or 20 kb span paired ends reads to order and join contigs into scaffold to accurately reconstruct the structure of a genome.